INDICATORS OF ANTIBODIES IgM AND IgG TO SARS-COV-2 IN RESIDENTS OF YAKUTSK AFTER RECOVERY FROM COVID-19

ABSTRACT

A study of IgM and IgG antibodies to SARS-COV-2 was carried out in 161 residents of Yakutsk at the age from 20 to 72 years old who had a new coronavirus infection COVID-19 from 3, 6, 9 and 12 months ago. The aim of the work was to assess the content of serum immunoglobulins IgM and IgG to SARS-COV-2 in persons who have had COVID-19, depending on the duration and severity of the disease. The intensity of the immune response was assessed using the coefficient of positivity (CP) as the ratio of the optical density of the sample to the critical value of the optical density. According to the results of the study, the seroprevalence in all 4 groups of patients with Covid-19 was 100%. Antibodies IgG and IgM to SARS-CoV-2 in those who had been ill with COVID-19 persisted up to 12 months and depended on the postcovid period, age and severity of lung lesions on CT.