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Case Series: Acute Hemorrhagic Encephalomyelitis After SARS-CoV-2 Vaccination.
Ancau, Mihai; Liesche-Starnecker, Friederike; Niederschweiberer, Johanna; Krieg, Sandro M; Zimmer, Claus; Lingg, Charlotte; Kumpfmüller, Daniela; Ikenberg, Benno; Ploner, Markus; Hemmer, Bernhard; Wunderlich, Silke; Mühlau, Mark; Knier, Benjamin.
  • Ancau M; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Liesche-Starnecker F; Department of Neuropathology, Institute of Pathology, Technical University of Munich, Munich, Germany.
  • Niederschweiberer J; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Krieg SM; Department of Neurosurgery, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Zimmer C; Department of Neuroradiology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Lingg C; Department of Anesthesiology and Intensive Care Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Kumpfmüller D; Department of Anesthesiology and Intensive Care Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Ikenberg B; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Ploner M; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Hemmer B; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Wunderlich S; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Mühlau M; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Knier B; Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
Front Neurol ; 12: 820049, 2021.
Article in English | MEDLINE | ID: covidwho-1709257
ABSTRACT
We present three cases fulfilling diagnostic criteria of hemorrhagic variants of acute disseminated encephalomyelitis (acute hemorrhagic encephalomyelitis, AHEM) occurring within 9 days after the first shot of ChAdOx1 nCoV-19. AHEM was diagnosed using magnetic resonance imaging, cerebrospinal fluid analysis and brain biopsy in one case. The close temporal association with the vaccination, the immune-related nature of the disease as well as the lack of other canonical precipitating factors suggested that AHEM was a vaccine-related adverse effect. We believe that AHEM might reflect a novel COVID-19 vaccine-related adverse event for which physicians should be vigilant and sensitized.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Topics: Vaccines / Variants Language: English Journal: Front Neurol Year: 2021 Document Type: Article Affiliation country: Fneur.2021.820049

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Topics: Vaccines / Variants Language: English Journal: Front Neurol Year: 2021 Document Type: Article Affiliation country: Fneur.2021.820049