Your browser doesn't support javascript.
WHO guidance on COVID-19 vaccine trial designs in the context of authorized COVID-19 vaccines and expanding global access: Ethical considerations.
Singh, Jerome Amir; Kochhar, Sonali; Wolff, Jonathan; Atuire, Caesar; Bhan, Anant; Emanuel, Ezekiel; Faden, Ruth; Ghimire, Prakash; Greco, Dirceu; Ho, Calvin; Moon, Suerie; Shamsi-Gooshki, Ehsan; Touré, Aissatou; Thomé, Beatriz; Smith, Maxwell J; Upshur, Ross E G.
  • Singh JA; Howard College School of Law, University of KwaZulu-Natal, Durban, South Africa; Scientific Advisory Group on Emergencies (SAGE), Academy of Science of South Africa (ASSAf), Pretoria, South Africa; Department of Clinical Public Health, Dalla Lana School of Public Health, University of Toronto, Toron
  • Kochhar S; Department of Global Health, University of Washington, Seattle, WA, USA; Global Healthcare Consulting, Delhi, India.
  • Wolff J; Blavatnik School of Government, University of Oxford, Oxford, UK.
  • Atuire C; Department of Philosophy and Classics, University of Ghana, Accra, Ghana.
  • Bhan A; Department of Community Medicine and Centre for Ethics, Yenepoya University, Mangalore, India.
  • Emanuel E; Global Initiatives and Healthcare Transformation Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Faden R; Johns Hopkins Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.
  • Ghimire P; Tribhuvan University, Kirtipur, Nepal.
  • Greco D; School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Ho C; Faculty of Law and Centre for Medical Ethics, University of Hong Kong, Hong Kong Special Administrative Region, China.
  • Moon S; International Relations and Political Science Department & Interdisciplinary Programmes, Global Health Centre, Graduate Institute of International and Development Studies, Geneva, Switzerland.
  • Shamsi-Gooshki E; Department of Medical Ethics, Tehran University of Medical Sciences, Tehran, Iran.
  • Touré A; Institut Pasteur, Dakar, Senegal.
  • Thomé B; Departamento de Medicina Preventiva, Universidade Federal de São Paulo, Rua Botucatu,Sao Paolo, Brazil.
  • Smith MJ; Faculty of Health Sciences, Western University, London, Ontario, Canada.
  • Upshur REG; Department of Family and Community Medicine and Dalla Lana School of Public Health University of Toronto, Toronto, Ontario, Canada.
Vaccine ; 40(14): 2140-2149, 2022 03 25.
Article in English | MEDLINE | ID: covidwho-1709280
ABSTRACT
While the degree of COVID-19 vaccine accessibility and uptake varies at both national and global levels, increasing vaccination coverage raises questions regarding the standard of prevention that ought to apply to different settings where COVID-19 vaccine trials are hosted. A WHO Expert Group has developed guidance on the ethical implications of conducting placebo-controlled trials in the context of expanding global COVID-19 vaccine coverage. The guidance also considers alternative trial designs to placebo controlled trials in the context of prototype vaccines, modified vaccines, and next generation vaccines.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Experimental Studies / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Vaccine Year: 2022 Document Type: Article

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Experimental Studies / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Vaccine Year: 2022 Document Type: Article