Misidentification of the SARS-CoV-2 Mu variant using commercial mutation screening assays.
Arch Virol
; 167(4): 1141-1144, 2022 Apr.
Article
in English
| MEDLINE | ID: covidwho-1709461
ABSTRACT
Detection of mutations by multiplex real-time RT-PCR is a widely used method for the screening of SARS-CoV-2 variants, but this method has several limitations. We describe three cases in which a Mu strain containing the mutation K417N was initially misclassified as the Beta variant. We recommend the detection of P681H to distinguish between these two variants. Our experience highlights the importance of keeping track of new variants and mutations in order to adapt the current workflows.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
Topics:
Variants
Limits:
Humans
Language:
English
Journal:
Arch Virol
Year:
2022
Document Type:
Article
Affiliation country:
S00705-022-05395-w
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