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Single-Layer Inverted Internal Limiting Membrane Flap Versus Conventional Peel for Small- or Medium-Sized Full-Thickness Macular Holes.
Chou, Hung-Da; Liu, Laura; Wang, Chung-Ting; Chen, Kuan-Jen; Wu, Wei-Chi; Hwang, Yih-Shiou; Chen, Yen-Po; Kang, Eugene Yu-Chuan; Chen, Yi-Hsing; Yeung, Ling; Lai, Chi-Chun.
  • Chou HD; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Liu L; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Wang CT; Department of Medical Education (C.-T.W.), Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.
  • Chen KJ; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Wu WC; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Hwang YS; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Chen YP; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University; Department of Ophthalmology (Y.-P.C.), New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan.
  • Kang EY; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Chen YH; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University.
  • Yeung L; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University; Department of Ophthalmology (L.Y., C.-C.L.), Chang Gung Memorial Hospital, Keelung, Taiwan.Chi-Chun Lai is currently practicing at the Department of Ophthalmology, Chang
  • Lai CC; From the Department of Ophthalmology (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., E.Y.-C.K.,Y.-H.C., C.-C.L.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (H.-D.C., L.L., K.-J.C., W.-C.W., Y.-S.H., Y.-P.C., E.Y.-C.K.,Y.-H.C., L.Y., C.-C.L.), Chang Gung University;
Am J Ophthalmol ; 235: 111-119, 2022 03.
Article in English | MEDLINE | ID: covidwho-1709798
ABSTRACT

PURPOSE:

To analyze the outcomes of using an internal limiting membrane (ILM) flap and the conventional ILM peel technique for small- or medium-sized full-thickness macular hole (FTMH) repair.

DESIGN:

Retrospective, interventional case series.

METHODS:

Eyes with an FTMH ≤400 µm that underwent vitrectomy with a single-layer inverted ILM flap (flap group, 55 eyes) or an ILM peel (peel group, 62 eyes) were enrolled. Best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) measurements were obtained preoperatively and at 1, 3, 6, and 12 months postoperatively.

RESULTS:

Primary hole closure was achieved in 54 (98%) and 60 (97%) eyes in the flap and peel groups, respectively. The preoperative and postoperative 12-month BCVA values were comparable between the groups but were significantly better in the flap than in the peel group at 1 month (mean ± SD logMAR 0.83 ± 0.43 vs 1.14 ± 0.50; P = .001), 3 months (0.58 ± 0.33 vs 0.82 ± 0.43; P = .002), and 6 months (0.56 ± 0.32 vs. 0.72 ± 0.48; P = .028). In the flap group, foveal gliosis was less common than in the peel group at 1 month (P = .030), and restored external limiting membrane and interdigitation zone was more common at 3 months (P = .046 and P < .001, respectively).

CONCLUSIONS:

The single-layer ILM flap and conventional ILM peel techniques both closed FTMHs and improved vision. ILM flaps were associated with better visual outcomes up to 6 months postoperatively and should be considered in FTMHs ≤400 µm.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Retinal Perforations Type of study: Diagnostic study / Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Language: English Journal: Am J Ophthalmol Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Retinal Perforations Type of study: Diagnostic study / Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Language: English Journal: Am J Ophthalmol Year: 2022 Document Type: Article