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Characterizing the COVID-19 Illness Experience to Inform the Study of Post-acute Sequelae and Recovery.
Santiago-Rodriguez, Edda I; Maiorana, Andres; Peluso, Michael J; Hoh, Rebecca; Tai, Viva; Fehrman, Emily A; Hernandez, Yanel; Torres, Leonel; Spinelli, Matthew A; Gandhi, Monica; Kelly, J Daniel; Martin, Jeffrey N; Henrich, Timothy J; Deeks, Steven G; Sauceda, John A.
  • Santiago-Rodriguez EI; Center for AIDS Prevention Studies, University of California, San Francisco, 550 16th Street, 3rd Floor, San Francisco, CA, 94158, USA.
  • Maiorana A; Center for AIDS Prevention Studies, University of California, San Francisco, 550 16th Street, 3rd Floor, San Francisco, CA, 94158, USA.
  • Peluso MJ; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Hoh R; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Tai V; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Fehrman EA; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Hernandez Y; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Torres L; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Spinelli MA; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Gandhi M; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Kelly JD; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Martin JN; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
  • Henrich TJ; Division of Experimental Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Deeks SG; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Sauceda JA; Center for AIDS Prevention Studies, University of California, San Francisco, 550 16th Street, 3rd Floor, San Francisco, CA, 94158, USA. john.sauceda@ucsf.edu.
Int J Behav Med ; 29(5): 610-623, 2022 Oct.
Article in English | MEDLINE | ID: covidwho-1712359
ABSTRACT

BACKGROUND:

There is an urgent need to fully understand the impact of variable COVID-19 experiences and the optimal management of post-acute sequelae of SARS-CoV-2 infection. We characterized the variability in the acute illness experience and ongoing recovery process from participants in a COVID-19 recovery cohort study in Northern California in 2020.

METHOD:

We completed 24 semi-structured in-depth interviews with adults with confirmed positive SARV-CoV-2 nucleic acid amplification test result, had recovered or were recovering from acute infection, and underwent serial evaluations. We purposefully sampled English- and Spanish-speaking adults with asymptomatic, mild, and severe symptomatic infection, including those who were hospitalized and those with HIV co-infection. We used a thematic analysis to analyze interviews and identify salient themes.

RESULTS:

After integrating the thematic analysis with clinical data, we identified key themes (1) across symptom profiles and severity, experiencing COVID-19 was associated with psychological distress; (2) symptomatic infection carried uncertainty in symptom presentation and ongoing recovery (e.g., long COVID); and (3) health information-seeking behavior was facilitated by access to medical care and uncertainty with the recovery process.

CONCLUSION:

Our data informs the emerging field of "long COVID" research and shows a need to provide information and continuous support to persons with post-acute sequelae to ensure they feel secure along the path to recovery.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Adult / Humans Language: English Journal: Int J Behav Med Journal subject: Behavioral Sciences Year: 2022 Document Type: Article Affiliation country: S12529-021-10045-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Adult / Humans Language: English Journal: Int J Behav Med Journal subject: Behavioral Sciences Year: 2022 Document Type: Article Affiliation country: S12529-021-10045-7