A Case of Salvage Maxillectomy for Recurrent Oral Cancer After Boron Neutron Capture Therapy During the COVID-19 Pandemic.
Anticancer Res
; 42(3): 1653-1657, 2022 Mar.
Article
in English
| MEDLINE | ID: covidwho-1716348
ABSTRACT
BACKGROUND:
During the COVID-19 pandemic, pedicle flaps instead of free flap transfer were recommended for head and neck reconstruction to reduce infection risk. Boron neutron-capture therapy in Japan was clinically approved in 2020 as a salvage radiotherapy for recurrent head and neck cancer following chemoradiotherapy. The efficacy and safety of salvage surgery following boron neutron-capture therapy remain unclear. CASE REPORT We describe a 57-year-old male with crT4aN0M0 oral cancer after three different forms of radiotherapy including boron neutron-capture therapy, treated by salvage partial maxillectomy with both buccal fat pad and nasoseptal flaps. His postsurgical course was successful, without tracheostomy, and he had no Clavien- Dindo grade 3 or 4 complications. The pathological diagnosis was T4a squamous cell carcinoma with a negative surgical margin. No recurrence or metastasis had occurred at 113 days postoperatively. No opioid consumption was needed postoperatively.CONCLUSION:
Pathological negative margins were achieved in this case and there were no severe complications. Further accrual of cases salvage surgery following boron neutron-capture therapy is required to clarify treatment strategies for recurrent head and neck cancer.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Mouth Neoplasms
/
Salvage Therapy
/
Squamous Cell Carcinoma of Head and Neck
/
COVID-19
/
Neoplasm Recurrence, Local
Type of study:
Case report
/
Observational study
/
Prognostic study
Limits:
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
English
Journal:
Anticancer Res
Year:
2022
Document Type:
Article
Affiliation country:
Anticanres.15642
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