Cell-cell communication analysis for single-cell RNA sequencing and its applications in carcinogenesis and COVID-19
Biosafety and Health
; 2022.
Article
in English
| ScienceDirect | ID: covidwho-1719403
ABSTRACT
Cell-cell communication is the basis of physiological processes and cell signals. The disease occurs when the cells do not adequately communicate and the messages are blocked. With ligand-receptor interaction databases and single-cell RNA sequencing (scRNA-seq) databases, we can detect intercellular signaling and reconstruct the cell-cell communications among different cell types. This review summarized the computational approaches for analyzing the cell-cell communication based on scRNA-seq data and discussed its applications in carcinogenesis and COVID-19. We believe that this review will accelerate the scRNA-seq data deciphering and facilitate the cell-cell communication studies for complex physiological processes, such as carcinogenesis and SARS-CoV-2 infection.
Full text:
Available
Collection:
Databases of international organizations
Database:
ScienceDirect
Language:
English
Journal:
Biosafety and Health
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS