Spillover of SARS-CoV-2 into novel wild hosts in North America: A conceptual model for perpetuation of the pathogen
Sci. Total Environ.
; (733)20200901.
Article
in English
| WHO COVID, ELSEVIER | ID: covidwho-1720888
ABSTRACT
There is evidence that the current outbreak of the novel coronavirus SARS-CoV-2, which causes COVID-19, is of animal origin. As with a number of zoonotic pathogens, there is a risk of spillover into novel hosts. Here, we propose a hypothesized conceptual model that illustrates the mechanism whereby the SARS-CoV-2 could spillover from infected humans to naive wildlife hosts in North America. This proposed model is premised on transmission of SARS-CoV-2 from human feces through municipal waste water treatment plants into the natural aquatic environment where potential wildlife hosts become infected. We use the existing literature on human coronaviruses, including SARS CoV, to support the potential pathways and mechanisms in the conceptual model. Although we focus on North America, our conceptual model could apply to other parts of the globe as well.
Full text:
Available
Collection:
International databases
Database:
WHO COVID
/
ELSEVIER
Type of study:
Prognostic study
Language:
English
Journal:
Sci. Total Environ.
Year:
2020
Document Type:
Article
Institution/Affiliation country:
USDA National Wildlife Research Center/United States
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