Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19.

Vaduganathan, Muthiah; Vardeny, Orly; Michel, Thomas; McMurray, John J V; Pfeffer, Marc A; Solomon, Scott D

Vaduganathan, Muthiah; Vardeny, Orly; Michel, Thomas; McMurray, John J V; Pfeffer, Marc A; Solomon, Scott D.

Vaduganathan M; From the Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston (M.V., T.M., M.A.P., S.D.S.); the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis (O.V.); and the British Heart Foundation Ca
Vardeny O; From the Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston (M.V., T.M., M.A.P., S.D.S.); the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis (O.V.); and the British Heart Foundation Ca
Michel T; From the Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston (M.V., T.M., M.A.P., S.D.S.); the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis (O.V.); and the British Heart Foundation Ca
McMurray JJV; From the Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston (M.V., T.M., M.A.P., S.D.S.); the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis (O.V.); and the British Heart Foundation Ca
Pfeffer MA; From the Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston (M.V., T.M., M.A.P., S.D.S.); the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis (O.V.); and the British Heart Foundation Ca
Solomon SD; From the Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston (M.V., T.M., M.A.P., S.D.S.); the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis (O.V.); and the British Heart Foundation Ca

N Engl J Med ; 382(17): 1653-1659, 2020 04 23.

Article in English | MEDLINE | ID: covidwho-1721759

Subject(s)

Angiotensin Receptor Antagonists/therapeutic use; Angiotensin-Converting Enzyme Inhibitors/therapeutic use; Betacoronavirus/metabolism; Coronavirus Infections/metabolism; Hypertension/drug therapy; Peptidyl-Dipeptidase A/metabolism; Pneumonia, Viral/metabolism; Renin-Angiotensin System/drug effects; Angiotensin Receptor Antagonists/pharmacology; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors/pharmacology; COVID-19; Coronavirus Infections/complications; Down-Regulation; Humans; Hypertension/complications; Pandemics; Pneumonia, Viral/complications; Renal Insufficiency, Chronic/complications; Renal Insufficiency, Chronic/drug therapy; SARS-CoV-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Renin-Angiotensin System / Angiotensin-Converting Enzyme Inhibitors / Coronavirus Infections / Peptidyl-Dipeptidase A / Angiotensin Receptor Antagonists / Betacoronavirus / Hypertension Topics: Long Covid Limits: Humans Language: English Journal: N Engl J Med Year: 2020 Document Type: Article

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