Diemer and Swanson Reply to "Considerations Before Using Pandemic as Instrument".
Am J Epidemiol
; 190(11): 2280-2283, 2021 11 02.
Article
in English
| MEDLINE | ID: covidwho-1722199
ABSTRACT
Dimitris and Platt (Am J Epidemiol. 2021;190(11)2275-2279) take on the challenging topic of using "shocks" such as the severe acute respiratory system coronavirus 2 (SARS-CoV-2) pandemic as instrumental variables to study the effect of some exposure on some outcome. Evoking our recent lived experiences, they conclude that the assumptions necessary for an instrumental variable analysis will often be violated and therefore strongly caution against such analyses. Here, we build upon this warranted caution while acknowledging that such analyses will still be pursued and conducted. We discuss strategies for evaluating or reasoning about when such an analysis is clearly inappropriate for a given research question, as well as strategies for interpreting study findings with special attention to incorporating plausible sources of bias in any conclusions drawn from a given finding.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pandemics
/
COVID-19
Type of study:
Experimental Studies
/
Prognostic study
/
Qualitative research
/
Systematic review/Meta Analysis
Limits:
Humans
Language:
English
Journal:
Am J Epidemiol
Year:
2021
Document Type:
Article
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