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Can Probiotics and Diet Promote Beneficial Immune Modulation and Purine Control in Coronavirus Infection?
Morais, Ana H A; Passos, Thais S; Maciel, Bruna L L; da Silva-Maia, Juliana K.
  • Morais AHA; Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
  • Passos TS; Biochemistry Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
  • Maciel BLL; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
  • da Silva-Maia JK; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Nutrients ; 12(6)2020 Jun 10.
Article in English | MEDLINE | ID: covidwho-1725886
ABSTRACT
Infection caused by the SARS-CoV-2 coronavirus worldwide has led the World Health Organization to declare a COVID-19 pandemic. Because there is no cure or treatment for this virus, it is emergingly urgent to find effective and validated methods to prevent and treat COVID-19 infection. In this context, alternatives related to nutritional therapy might help to control the infection. This narrative review proposes the importance and role of probiotics and diet as adjunct alternatives among the therapies available for the treatment of this new coronavirus. This review discusses the relationship between intestinal purine metabolism and the use of Lactobacillus gasseri and low-purine diets, particularly in individuals with hyperuricemia, as adjuvant nutritional therapies to improve the immune system and weaken viral replication, assisting in the treatment of COVID-19. These might be promising alternatives, in addition to many others that involve adequate intake of vitamins, minerals and bioactive compounds from food.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Probiotics / Diet / Immunomodulation / Betacoronavirus Type of study: Prognostic study / Reviews Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: Nu12061737

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Probiotics / Diet / Immunomodulation / Betacoronavirus Type of study: Prognostic study / Reviews Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: Nu12061737