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Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study.
Katoto, Patrick D M C; Parker, Saahier; Coulson, Nancy; Pillay, Nirvana; Cooper, Sara; Jaca, Anelisa; Mavundza, Edison; Houston, Gregory; Groenewald, Candice; Essack, Zaynab; Simmonds, Jane; Shandu, Londiwe Deborah; Couch, Marilyn; Khuzwayo, Nonkululeko; Ncube, Nobukhosi; Bhengu, Phelele; Rooyen, Heidi van; Wiysonge, Charles Shey.
  • Katoto PDMC; Cochrane South Africa, South African Medical Research Council, Cape Town 7501, South Africa.
  • Parker S; Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 7505, South Africa.
  • Coulson N; Centre for General Medicine and Global Health, Department of Medicine, University of Cape Town, Cape Town 7505, South Africa.
  • Pillay N; Human Sciences Research Council, Cape Town 8000, South Africa.
  • Cooper S; The Sarraounia Public Health Trust, Johannesburg 2193, South Africa.
  • Jaca A; Wits Mining Institute, University of the Witwatersrand, Johannesburg 2050, South Africa.
  • Mavundza E; The Sarraounia Public Health Trust, Johannesburg 2193, South Africa.
  • Houston G; School of Public Health, University of the Witwatersrand, Johannesburg 2050, South Africa.
  • Groenewald C; Cochrane South Africa, South African Medical Research Council, Cape Town 7501, South Africa.
  • Essack Z; Cochrane South Africa, South African Medical Research Council, Cape Town 7501, South Africa.
  • Simmonds J; Cochrane South Africa, South African Medical Research Council, Cape Town 7501, South Africa.
  • Shandu LD; Human Sciences Research Council, Cape Town 8000, South Africa.
  • Couch M; Human Sciences Research Council, Cape Town 8000, South Africa.
  • Khuzwayo N; Department of Psychology, Rhodes University, Grahamstown 6140, South Africa.
  • Ncube N; Human Sciences Research Council, Cape Town 8000, South Africa.
  • Bhengu P; South African Research Ethics Training Initiative (SARETI), University of KwaZulu-Natal, Pietermaritzburg 3209, South Africa.
  • Rooyen HV; South African Medical Research Council, Cape Town 7501, South Africa.
  • Wiysonge CS; Human Sciences Research Council, Cape Town 8000, South Africa.
Vaccines (Basel) ; 10(3)2022 Feb 25.
Article in English | MEDLINE | ID: covidwho-1726054
ABSTRACT
South Africa launched a mass COVID-19 vaccination campaign in May 2021, targeting 40 million adults. Understanding predictors of COVID-19 vaccine intentions was required to achieve this goal. We conducted a population-based survey in June-July 2021 using the WHO Behavioral and Social Drivers (BeSD) of COVID-19 Vaccination tool to determine predictors of vaccine hesitancy, defined as intention to refuse or uncertainty whether to accept COVID-19 vaccination. There were 1193 participants, mean age 39 (standard deviation 15) years, and 53% women, of whom 58% trusted information provided by healthcare workers and 32% were vaccine hesitant. Independent predictors of vaccine hesitancy included concerns about side effects (odds ratio (OR) 11.41; 95% confidence interval (CI) 3.5-50.80), lack of access to the online vaccine registration platform (OR 4.75; CI 2.15-10.37), distrust of government (OR 3.0; CI 1.33-6.77), belief in conspiracy theories (OR 3.01; CI 1.32-6.77), having no monthly income (OR 1.84; CI 1.12-3.07), and depending on someone else to make vaccination decision (OR 2.47; CI 1.06-5.77). We identified modifiable predictors of vaccine hesitancy at the start of South Africa's COVID-19 vaccination rollout. These factors should be addressed by different stakeholders involved in the national immunization program through tailored communication and other effective strategies that increase vaccine literacy, reach low-income households, and engender confidence in government.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Topics: Vaccines Language: English Year: 2022 Document Type: Article Affiliation country: Vaccines10030353

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Topics: Vaccines Language: English Year: 2022 Document Type: Article Affiliation country: Vaccines10030353