Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants

Zhang, Yali, Wei, Min, Wu, Yangtao, Wang, Juan, Hong, Yuting, Huang, Yang, Yuan, Lunzhi, Ma, Jian, Wang, Kai, Wang, Shaojuan, Shi, Yang, Wang, Zikang, Guo, Huilin, Xiao, Jin, Yang, Chuanlai, Ye, Jianghui, Chen, Jijing, Liu, Yuxi, Fu, Baorong, Lan, Miaolin, Gong, Peixuan, Huang, Zehong, Su, Yingying, Chen, Yixin, Zhang, Tianying, Zhang, Jun, Zhu, Huachen, Yu, Hai, Yuan, Quan, Cheng, Tong, Guan, Yi, Xia, Ningshao

Zhang, Yali, Wei, Min, Wu, Yangtao, Wang, Juan, Hong, Yuting, Huang, Yang, Yuan, Lunzhi, Ma, Jian, Wang, Kai, Wang, Shaojuan, Shi, Yang, Wang, Zikang, Guo, Huilin, Xiao, Jin, Yang, Chuanlai, Ye, Jianghui, Chen, Jijing, Liu, Yuxi, Fu, Baorong, Lan, Miaolin, Gong, Peixuan, Huang, Zehong, Su, Yingying, Chen, Yixin, Zhang, Tianying, Zhang, Jun, Zhu, Huachen, Yu, Hai, Yuan, Quan, Cheng, Tong, Guan, Yi, Xia, Ningshao.

Cell reports ; 2022.

Article in English | EuropePMC | ID: covidwho-1728589

ABSTRACT

ABSTRACT

Zhang et al. show in vitro cross-species infectivity and neutralization-escape characteristics of 153 SARS-CoV-2 RBD mutants and 11 globally circulating VOC/VOI variants. They reveal an association between enhanced cross-species infection potential and the current cumulative prevalence of mutations, which can inform surveillance and forecasting of SARS-CoV-2 spike mutations.

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Collection: Databases of international organizations Database: EuropePMC Type of study: Randomized controlled trials Topics: Variants Language: English Journal: Cell reports Year: 2022 Document Type: Article

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