High mortality among hospitalized adult patients with COVID-19 pneumonia in Peru: A single centre retrospective cohort study.
PLoS One
; 17(3): e0265089, 2022.
Article
in English
| MEDLINE | ID: covidwho-1731605
ABSTRACT
BACKGROUND:
Peru is the country with the world's highest COVID-19 death rate per capita. Characteristics associated with increased mortality among adult patients with COVID-19 pneumonia in this setting are not well described.METHODS:
Retrospective, single-center cohort study including 1537 adult patients hospitalized with a diagnosis of SARS-CoV-2 pneumonia between May 2020 and August 2020 at a national hospital in Lima, Peru. The primary outcome measure was in-hospital mortality.RESULTS:
In-hospital mortality was 49.71%. The mean age was 60 ± 14.25 years, and 68.38% were males. We found an association between mortality and inflammatory markers, mainly leukocytes, D-dimer, lactate dehydrogenase, C-reactive protein and ferritin. A multivariate model adjusted for age, hypertension, diabetes mellitus, and corticosteroid use demonstrated that in-hospital mortality was associated with greater age (RR 2.01, 95%CI 1.59-2.52) and a higher level of oxygen requirement (RR 2.77, 95%CI 2.13-3.62).Conclusions:
In-hospital mortality among COVID-19 patients in Peru is high and is associated with greater age and higher oxygen requirements.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Hospitalization
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
South America
/
Peru
Language:
English
Journal:
PLoS One
Journal subject:
Science
/
Medicine
Year:
2022
Document Type:
Article
Affiliation country:
Journal.pone.0265089
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