Differences between COVID-19-induced acute kidney injury and chronic kidney disease patients.
J Bras Nefrol
; 44(2): 155-163, 2022.
Article
in English, Portuguese
| MEDLINE | ID: covidwho-1731637
ABSTRACT
INTRODUCTION:
This article describes the main differences between COVID-19-induced acute kidney injury (AKI-COVID19) in patients with previous normal renal function (AKI-NRF) and those with chronic kidney disease (AKI-CKD) treated in a high complexity clinic in Barranquilla (Colombia). MATERIAL ANDMETHODS:
The patients included in this study (n 572) were those with a positive diagnosis of COVID-19 confirmed by detection of a positive PCR for SARS-CoV-2. Of these patients, 188 developed AKI during their hospital stay. Patients' epidemiological data, serum parameters, and clinical frailty status were recorded. Statistical analysis and comparison among AKI-NRF, AKI-CKD, and non-AKI patients were performed.RESULTS:
The incidence of COVID-19-induced AKI was 33%, with the majority classified as AKIN 1, 16% requiring renal replacement therapy, and AKI-COVID19 mortality of 68%. A significantly higher prevalence of hypertension, cardiac disease, and serum reactive C-protein and lower albumin values in AKI-CKD patients was recorded. Mortality rate, invasive ventilation requirement, and D-dimer levels were significantly higher in AKI-NRF patients.CONCLUSION:
Different clinical patterns between AKI-NRF and AKI-CKD were documented.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Renal Insufficiency, Chronic
/
Acute Kidney Injury
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
/
Portuguese
Journal:
J Bras Nefrol
Journal subject:
Nephrology
Year:
2022
Document Type:
Article
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