The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study
Annali dell'Istituto Superiore di Sanita
; 57(4):272-285, 2021.
Article
in English
| ProQuest Central | ID: covidwho-1733123
ABSTRACT
Introduction. This study aimed to estimate the incidence of SARS-CoV-2 infection among pregnant women during the first pandemic wave in Italy, and to describe COVID-19 disease characteristics and maternal and perinatal outcomes. Materials and methods. National population-based prospective cohort study collecting information on women with SARS-CoV-2 diagnosis, confirmed within 7 days from hospital admission. Results. The national SARS-CoV-2 rate was 6.04 per 1,000 births (95% CI 5.62-6.49) among pregnant women and 7.54 (95% CI 7.47-7.61) among women in reproductive age. 72.1% of the cohort developed mild COVID-19 disease without pneumonia nor need for ventilatory support. Severe disease was significantly associated with women’s previous comorbidities (OR 2.55;95% CI 0.98-6.90), obesity (OR 4.76;95% CI 1.79-12.66) and citizenship from High Migration Pressure Countries (OR 3.43;95% CI 1.27-9.25). Conclusions. During the first pandemic wave in Italy, the SARS-CoV-2 rate among pregnant women was lower compared to that detected among women of reproductive age, and risks of severe COVID-19 disease and adverse maternal and perinatal outcomes were rare.
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Collection:
Databases of international organizations
Database:
ProQuest Central
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Annali dell'Istituto Superiore di Sanita
Year:
2021
Document Type:
Article
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