Existence of immunological memory response in true sero-negative individuals post COVID-19 molecular diagnosis.

Lustig, Yaniv; Mendelson, Ella; Mandelboim, Michal; Biber, Asaf; Levin, Einav G; Cohen, Carmit; Regev-Yochay, Gili; Schwartz, Eli

Lustig, Yaniv; Mendelson, Ella; Mandelboim, Michal; Biber, Asaf; Levin, Einav G; Cohen, Carmit; Regev-Yochay, Gili; Schwartz, Eli.

Lustig Y; Central Virology Laboratory, Public Health Services, Ministry of Health, Sheba Medical Center, Tel-Hashomer, Israel.
Mendelson E; Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Mandelboim M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Biber A; Central Virology Laboratory, Public Health Services, Ministry of Health, Sheba Medical Center, Tel-Hashomer, Israel.
Levin EG; Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Cohen C; Central Virology Laboratory, Public Health Services, Ministry of Health, Sheba Medical Center, Tel-Hashomer, Israel.
Regev-Yochay G; Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Schwartz E; Sackler Faculty of Medicine, Tel-Aviv University, Israel.

Clin Infect Dis ; 2022 Mar 10.

Article in English | MEDLINE | ID: covidwho-1735546

ABSTRACT

ABSTRACT

Approximately 1-8% of individuals do not develop antibodies following SARS-CoV-2 infection (sero-negatives). One BNT162b2 dose resulted in potent humoral response in 14 sero-negatives and 15 sero-positives, significantly higher than the response of 15 naïve-individuals, to two doses suggesting that COVID-19 provoked a memory response in individuals without detectable antibodies.

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Full text: Available Collection: International databases Database: MEDLINE Topics: Long Covid / Vaccines Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid

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