Understanding ethnic inequalities in stillbirth rates: a UK population-based cohort study.
BMJ Open
; 12(2): e057412, 2022 03 09.
Article
in English
| MEDLINE | ID: covidwho-1736072
ABSTRACT
OBJECTIVES:
To investigate inequalities in stillbirth rates by ethnicity to facilitate development of initiatives to target those at highest risk.DESIGN:
Population-based perinatal mortality surveillance linked to national birth and death registration (Mothers and Babies Reducing Risk through Audits and Confidential Enquiries across the UK).SETTING:
UK.PARTICIPANTS:
4 391 569 singleton births at ≥24+0 weeks gestation between 2014 and 2019. MAIN OUTCOMEMEASURES:
Stillbirth rate difference per 1000 total births by ethnicity.RESULTS:
Adjusted absolute differences in stillbirth rates were higher for babies of black African (3.83, 95% CI 3.35 to 4.32), black Caribbean (3.60, 95% CI 2.65 to 4.55) and Pakistani (2.99, 95% CI 2.58 to 3.40) ethnicities compared with white ethnicities. Higher proportions of babies of Bangladeshi (42%), black African (39%), other black (39%) and black Caribbean (37%) ethnicities were from most deprived areas, which were associated with an additional risk of 1.50 stillbirths per 1000 births (95% CI 1.32 to 1.67). Exploring primary cause of death, higher stillbirth rates due to congenital anomalies were observed in babies of Pakistani, Bangladeshi and black African ethnicities (range 0.63-1.05 per 1000 births) and more placental causes in black ethnicities (range 1.97 to 2.24 per 1000 births). For the whole population, over 40% of stillbirths were of unknown cause; however, this was particularly high for babies of other Asian (60%), Bangladeshi (58%) and Indian (52%) ethnicities.CONCLUSIONS:
Stillbirth rates declined in the UK, but substantial excess risk of stillbirth persists among babies of black and Asian ethnicities. The combined disadvantage for black, Pakistani and Bangladeshi ethnicities who are more likely to live in most deprived areas is associated with considerably higher rates. Key causes of death were congenital anomalies and placental causes. Improved strategies for investigation of stillbirth causes are needed to reduce unexplained deaths so that interventions can be targeted to reduce stillbirths.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Ethnicity
/
Stillbirth
Type of study:
Cohort study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Female
/
Humans
/
Infant
/
Pregnancy
Country/Region as subject:
Europa
Language:
English
Journal:
BMJ Open
Year:
2022
Document Type:
Article
Affiliation country:
Bmjopen-2021-057412
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