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[An impact of COVID-19 on the course of epilepsy]. / Vliyanie COVID-19 na techenie epilepsii.
Odincova, G V; Nezdorovin, O V; Nezdorovina, V G.
  • Odincova GV; Polenov Neurosurgical Institute - a branch of Almazov National Medical Research Centre, St. Petersburg, Russia.
  • Nezdorovin OV; Polenov Neurosurgical Institute - a branch of Almazov National Medical Research Centre, St. Petersburg, Russia.
  • Nezdorovina VG; Polenov Neurosurgical Institute - a branch of Almazov National Medical Research Centre, St. Petersburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova ; 122(2): 101-106, 2022.
Article in Russian | MEDLINE | ID: covidwho-1737453
ABSTRACT
To compare an impact of coronavirus disease and Sputnik V COVID-19 vaccine on the dynamics of epilepsy. The study is part of the ongoing «Epilepsy and COVID-19¼ independent research which recruited patients with epilepsy into two groups group 1 - COVID-19 survivors and group 2 - patients vaccinated with a COVID-19 vaccine. The study compares two clinical cases seizure recurrence with COVID-19 disease in a young patient and good tolerability of vaccination in a female elderly patient following surgical management of pharmacoresistant epilepsy with concomitant pathology. In group 1, a 32-year-old patient with idiopathic generalized epilepsy and 3-year seizure remission had generalized seizure recurrence with electroencephalographic deterioration against the backdrop of mild COVID-19. In group 2, a 59-year-old patient, with focal pharmacoresistant epilepsy, and 3-year seizure remission after surgical management, and comorbid endocrine dysfunction showed no side-effects with Sputnik V COVID-19 vaccination and maintained clinical and electroencephalographic remission. The study revealed that the Sputnik V vaccine was well tolerated, and that seizure remission was maintained after epilepsy surgery in an elderly patient with comorbidity, as well as there was the possibility of seizure recurrence in younger patients with mild COVID-19. The findings will aid practitioners in making decisions on how to manage epilepsy patients. More study into the impact of the disease and COVID-19 vaccination on epilepsy dynamics in a larger sample is required.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epilepsy / COVID-19 Type of study: Case report / Experimental Studies / Prognostic study / Randomized controlled trials Topics: Long Covid / Vaccines Limits: Adult / Aged / Female / Humans / Middle aged Language: Russian Journal: Zh Nevrol Psikhiatr Im S S Korsakova Journal subject: Neurology / Psychiatry Year: 2022 Document Type: Article Affiliation country: Jnevro2022122021101

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epilepsy / COVID-19 Type of study: Case report / Experimental Studies / Prognostic study / Randomized controlled trials Topics: Long Covid / Vaccines Limits: Adult / Aged / Female / Humans / Middle aged Language: Russian Journal: Zh Nevrol Psikhiatr Im S S Korsakova Journal subject: Neurology / Psychiatry Year: 2022 Document Type: Article Affiliation country: Jnevro2022122021101