Diagnostic Value of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Patients with Severe COVID-19 - 7 PLADs, China, January 21-February 10, 2020.

ABSTRACT

What is already known about this topic? Coronavirus disease 2019 (COVID-19) causes symptoms ranging from mild to severe. Indicators for identifying severe COVID-19 infection have not been well identified, especially for young patients. What is added by this report? Both neutrophil-lymphocyte ratio (NLR) [area under curve (AUC) 0.80; the odds ratios (OR) and 95% confidence intervals (95% CI) 1.30 (1.13-1.50)] and platelet-lymphocyte ratio (PLR) [AUC 0.87; OR (95% CI) 1.05 (1.01-1.09)] were determined to be indicators for recognition of patients with severe COVID-19 in young patients less than age 40. What are the implications for public health practice? NLR and PLR are useful indicators for identifying patients with severe COVID-19, especially in young patients less than age 40.