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When cyclin-dependent kinases meet viral infections, including SARS-CoV-2.
Yan, Yan; Tang, Yan-Dong; Zheng, Chunfu.
  • Yan Y; Center of Clinical Laboratory, The Fifth People's Hospital of Wuxi, Affiliated Hospital of Jiangnan University, Wuxi, China.
  • Tang YD; Department of Immunology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
  • Zheng C; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, China.
J Med Virol ; 94(7): 2962-2968, 2022 07.
Article in English | MEDLINE | ID: covidwho-1739192
ABSTRACT
Cyclin-dependent kinases (CDKs) are protein kinases that play a key role in cell division and transcriptional regulation. Recent studies have demonstrated the critical roles of CDKs in various viral infections. However, the molecular processes underpinning CDKs' roles in viral infection and host antiviral defense are unknown. This minireview briefly overviews CDKs' functions and highlights the most recent discoveries of CDKs' emerging roles during viral infections, thereby providing a scientific and theoretical foundation for antiviral regulation and shedding light on developing novel drug targets and therapeutic strategies against viral infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Diseases / COVID-19 Limits: Humans Language: English Journal: J Med Virol Year: 2022 Document Type: Article Affiliation country: Jmv.27719

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Diseases / COVID-19 Limits: Humans Language: English Journal: J Med Virol Year: 2022 Document Type: Article Affiliation country: Jmv.27719