Evaluation of Febrile Seizure Diagnoses Associated With COVID-19.
J Child Neurol
; 37(5): 410-415, 2022 04.
Article
in English
| MEDLINE | ID: covidwho-1741827
ABSTRACT
BACKGROUND/OBJECTIVES:
Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be associated with febrile seizures, but the overall frequency and outcomes are unknown. The objectives of this study are to (1) determine the frequency of pediatric subjects diagnosed with febrile seizures and COVID-19, (2) evaluate patient characteristics, and (3) describe the treatments (medications and need for invasive mechanical ventilation) applied.METHODS:
This was a retrospective study utilizing TriNetX electronic health record data. We included subjects ranging from 0 to 5 years of age with a diagnosis of febrile seizures (R56.00, R56.01) and COVID-19 (U07.1). We extracted the following data age, race, ethnicity, diagnostic codes, medications, laboratory results, and procedures.RESULTS:
During this study period, 8854 pediatric subjects aged 0-5 years were diagnosed with COVID-19 among 34 health care organizations and 44 (0.5%) were also diagnosed with febrile seizures (simple, 30 [68.2%]; complex, 14 [31.8%]). The median age was 1.5 years (1, 2), there were no reported epilepsy diagnoses, and a proportion required hospitalization (11; 25.0%) and critical care services (4; 9.1%).CONCLUSIONS:
COVID-19 infections in children can be associated with febrile seizures. In our study, 0.5% of COVID-19 subjects were diagnosed with febrile seizures and approximately 9% of subjects were reported to require critical care services. Febrile seizures, although serious, are not a commonly diagnosed neurologic manifestation of COVID-19.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Seizures, Febrile
/
COVID-19
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
Topics:
Long Covid
Limits:
Child
/
Child, preschool
/
Humans
/
Infant
/
Infant, Newborn
Language:
English
Journal:
J Child Neurol
Journal subject:
Neurology
/
Pediatrics
Year:
2022
Document Type:
Article
Affiliation country:
08830738221086863
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