Fever, Tachypnea, and Monocyte Distribution Width Predicts Length of Stay for Patients with COVID-19: A Pioneer Study.
J Pers Med
; 12(3)2022 Mar 12.
Article
in English
| MEDLINE | ID: covidwho-1742521
ABSTRACT
(1) Background:
Our study investigated whether monocyte distribution width (MDW) could be used in emergency department (ED) settings as a predictor of prolonged length of stay (LOS) for patients with COVID-19. (2)Methods:
A retrospective cohort study was conducted; patients presenting to the ED of an academic hospital with confirmed COVID-19 were enrolled. Multivariable logistic regression models were used to obtain the odds ratios (ORs) for predictors of an LOS of >14 days. A validation study for the association between MDW and cycle of threshold (Ct) value was performed. (3)Results:
Fever > 38 °C (OR 2.82, 95% CI, 1.13-7.02, p = 0.0259), tachypnea (OR 4.76, 95% CI, 1.67-13.55, p = 0.0034), and MDW ≥ 21 (OR 5.67, 95% CI, 1.19-27.10, p = 0.0269) were robust significant predictors of an LOS of >14 days. We developed a new scoring system in which patients were assigned 1 point for fever > 38 °C, 2 points for tachypnea > 20 breath/min, and 3 points for MDW ≥ 21. The optimal cutoff was a score of ≥2. MDW was negatively associated with Ct value (ß -0.32 per day, standard error = 0.12, p = 0.0099). (4)Conclusions:
Elevated MDW was associated with a prolonged LOS.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Jpm12030449
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