Metformin: Sex/Gender Differences in Its Uses and Effects-Narrative Review.
Medicina (Kaunas)
; 58(3)2022 Mar 16.
Article
in English
| MEDLINE | ID: covidwho-1742545
ABSTRACT
Metformin (MTF) occupies a major and fundamental position in the therapeutic management of type 2 diabetes mellitus (T2DM). Gender differences in some effects and actions of MTF have been reported. Women are usually prescribed lower MTF doses compared to men and report more gastrointestinal side effects. The incidence of cardiovascular events in women on MTF has been found to be lower to that of men on MTF. Despite some promising results with MTF regarding pregnancy rates in women with PCOS, the management of gestational diabetes, cancer prevention or adjunctive cancer treatment and COVID-19, most robust meta-analyses have yet to confirm such beneficial effects.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Polycystic Ovary Syndrome
/
Diabetes Mellitus, Type 2
/
COVID-19 Drug Treatment
/
Metformin
Type of study:
Experimental Studies
/
Observational study
/
Reviews
Topics:
Long Covid
Limits:
Female
/
Humans
/
Male
/
Pregnancy
Language:
English
Journal subject:
Medicine
Year:
2022
Document Type:
Article
Affiliation country:
Medicina58030430
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