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Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19.
Tabarsi, Payam; Sharifynia, Somayeh; Pourabdollah Toutkaboni, Mihan; Abtahian, Zahra; Rahdar, Mohammad; Mirahmadian, Arefeh Sadat; Hakamifard, Atousa.
  • Tabarsi P; Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Sharifynia S; Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Pourabdollah Toutkaboni M; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Abtahian Z; Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Rahdar M; Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mirahmadian AS; Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Hakamifard A; Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Case Rep Med ; 2022: 8114388, 2022.
Article in English | MEDLINE | ID: covidwho-1745619
ABSTRACT
Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal etiology of Aspergillus flavus and Rhizopus arrhizus in case 1 and Aspergillus fumigatus and Rhizopus arrhizus in case 2. Both patients received liposomal amphotericin B then posaconazole combined with aggressive surgical debridement of necrotic tissues with a favorable clinical outcome. Mixed etiology AIFR can influence the outcome; hence, further studies are required upon this new threat.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Etiology study / Prognostic study Language: English Journal: Case Rep Med Year: 2022 Document Type: Article Affiliation country: 2022

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Etiology study / Prognostic study Language: English Journal: Case Rep Med Year: 2022 Document Type: Article Affiliation country: 2022