Your browser doesn't support javascript.
Detection techniques for epitranscriptomic marks.
Ofusa, Ken; Chijimatsu, Ryota; Ishii, Hideshi.
  • Ofusa K; Food and Life-Science Laboratory, Prophoenix Division, Idea Consultants, Inc., Osaka, Japan.
  • Chijimatsu R; Department of Medical Data Science, Center of Medical Innovation and Translational Research, Osaka University Graduate School of Medicine, Suita, Japan.
  • Ishii H; Department of Medical Data Science, Center of Medical Innovation and Translational Research, Osaka University Graduate School of Medicine, Suita, Japan.
Am J Physiol Cell Physiol ; 322(4): C787-C793, 2022 04 01.
Article in English | MEDLINE | ID: covidwho-1807579
ABSTRACT
Similar to epigenetic DNA modification, RNA can be methylated and altered for stability and processing. RNA modifications, namely, epitranscriptomes, involve the following three functions writing, erasing, and reading of marks. Methods for measurement and position detection are useful for the assessment of cellular function and human disease biomarkers. After pyrimidine 5-methylcytosine was reported for the first time a hundred years ago, numerous techniques have been developed for studying nucleotide modifications, including RNAs. Recent studies have focused on high-throughput and direct measurements for investigating the precise function of epitranscriptomes, including the characterization of severe acute respiratory syndrome coronavirus 2. The current study presents an overview of the development of detection techniques for epitranscriptomic marks and briefs about the recent progress in this field.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Transcriptome / COVID-19 Limits: Humans Language: English Journal: Am J Physiol Cell Physiol Journal subject: Physiology Year: 2022 Document Type: Article Affiliation country: Ajpcell.00460.2021

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Transcriptome / COVID-19 Limits: Humans Language: English Journal: Am J Physiol Cell Physiol Journal subject: Physiology Year: 2022 Document Type: Article Affiliation country: Ajpcell.00460.2021