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The domiNO effect turns macrophage activation deadly.
Robertson, Shelly J; Best, Sonja M.
  • Robertson SJ; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
  • Best SM; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. Electronic address: sbest@niaid.nih.gov.
Immunity ; 55(3): 382-384, 2022 03 08.
Article in English | MEDLINE | ID: covidwho-1747889
ABSTRACT
Macrophage activation is essential for effective immunity to infection but can also contribute to disease through incompletely understood mechanisms. In this issue of Immunity, Simpson et al. reveal that death of activated macrophages integrates extrinsic and intrinsic pathways of apoptosis that contribute to damaging host responses.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Interferon-gamma / Macrophage Activation Type of study: Experimental Studies Language: English Journal: Immunity Journal subject: Allergy and Immunology Year: 2022 Document Type: Article Affiliation country: J.immuni.2022.02.010

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Interferon-gamma / Macrophage Activation Type of study: Experimental Studies Language: English Journal: Immunity Journal subject: Allergy and Immunology Year: 2022 Document Type: Article Affiliation country: J.immuni.2022.02.010