Coronavirus disease (COVID-19) and the endothelium

ABSTRACT

The most commonly reported symptoms by patients affected by coronavirus disease 2019 (COVID-19) are fatigue, fever, and respiratory distress. However, other major changes observed in COVID-19 patients such as high blood pressure, thrombosis, and pulmonary embolism seem to suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is targeting the endothelium, one of the largest organs in the human body. This chapter reports on the role of the endothelium as a target of SARS-CoV-2. © 2021 Elsevier Inc. All rights reserved.