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COVID-19: autoimmunity, multisystemic inflammation and autoimmune rheumatic patients.
Szekanecz, Zoltán; Balog, Attila; Constantin, Tamás; Czirják, László; Géher, Pál; Kovács, László; Kumánovics, Gábor; Nagy, György; Rákóczi, Éva; Szamosi, Szilvia; Szucs, Gabriella; Vályi-Nagy, István.
  • Szekanecz Z; Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Balog A; Department of Rheumatology and Immunology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
  • Constantin T; 2nd Department of Paediatrics, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
  • Czirják L; Department of Rheumatology and Immunology, Faculty of Medicine, University of Pécs, Pécs, Hungary.
  • Géher P; Department of Rheumatology and Clinical Immunology, Semmelweis University, Budapest, Hungary.
  • Kovács L; Department of Rheumatology and Immunology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
  • Kumánovics G; Department of Rheumatology and Immunology, Faculty of Medicine, University of Pécs, Pécs, Hungary.
  • Nagy G; Departments of Rheumatology and Clinical Immunology, Genetics, Cell and Immunobiology and Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary.
  • Rákóczi É; Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Szamosi S; Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Szucs G; Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Vályi-Nagy I; National Institute of Haematology and Infectious Diseases, Budapest, Hungary.
Expert Rev Mol Med ; 24: e13, 2022 03 15.
Article in English | MEDLINE | ID: covidwho-1751544
ABSTRACT
Coronavirus disease 2019 (COVID-19) is associated with autoimmunity and systemic inflammation. Patients with autoimmune rheumatic and musculoskeletal disease (RMD) may be at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, based on evidence from the literature, as well as international scientific recommendations, we review the relationships between COVID-19, autoimmunity and patients with autoimmune RMDs, as well as the basics of a multisystemic inflammatory syndrome associated with COVID-19. We discuss the repurposing of pharmaceutics used to treat RMDs, the principles for the treatment of patients with autoimmune RMDs during the pandemic and the main aspects of vaccination against SARS-CoV-2 in autoimmune RMD patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Musculoskeletal Diseases / COVID-19 / COVID-19 Drug Treatment Type of study: Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Expert Rev Mol Med Journal subject: Molecular Biology Year: 2022 Document Type: Article Affiliation country: Erm.2022.10

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Musculoskeletal Diseases / COVID-19 / COVID-19 Drug Treatment Type of study: Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Expert Rev Mol Med Journal subject: Molecular Biology Year: 2022 Document Type: Article Affiliation country: Erm.2022.10