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Fatal SARS-CoV-2-Associated Panton-Valentine Leukocidin-producing Staphylococcal Bacteremia: A Nationwide Multicenter Cohort Study.
Nygaard, Ulrikka; Petersen, Andreas; Larsen, Anders Rhod; Rytter, Maren Johanne Heilskov; Hartling, Ulla; Kirkby, Nikolai; Hansen, Rikke Nymark; Nielsen, Allan Bybeck; Lundstrøm, Kaare; Holm, Mette; Vissing, Nadja Hawwa.
  • Nygaard U; From the Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen.
  • Petersen A; Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen.
  • Larsen AR; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen.
  • Rytter MJH; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen.
  • Hartling U; Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen.
  • Kirkby N; Department of Pediatrics and Adolescent Medicine, Slagelse Sygehus, Slagelse.
  • Hansen RN; Department of Paediatrics and Adolescent Medicine, Odense University Hospital, Odense.
  • Nielsen AB; Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen.
  • Lundstrøm K; Department of Paediatrics and Adolescent Medicine, Aalborg University Hospital.
  • Holm M; From the Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen.
  • Vissing NH; From the Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen.
Pediatr Infect Dis J ; 41(4): e142-e145, 2022 04 01.
Article in English | MEDLINE | ID: covidwho-1752202
ABSTRACT
We reviewed all cases of Panton-Valentine leukocidin-producing Staphylococcus aureus (PVL-SA) bacteremia in Danish children between 2016 and 2021. We found 2 fatal cases with preceding viral prodrome due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the usual benign course of SARS-CoV-2 infection in children, awareness of possible superinfection with PVL-SA in a child with rapid deterioration is crucial to ensure adequate treatment, including antimicrobial drugs with antitoxin effect.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Staphylococcal Infections / Staphylococcus aureus / Bacterial Toxins / Bacteremia / Exotoxins / SARS-CoV-2 / COVID-19 / Leukocidins Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: English Journal: Pediatr Infect Dis J Journal subject: Communicable Diseases / Pediatrics Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Staphylococcal Infections / Staphylococcus aureus / Bacterial Toxins / Bacteremia / Exotoxins / SARS-CoV-2 / COVID-19 / Leukocidins Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: English Journal: Pediatr Infect Dis J Journal subject: Communicable Diseases / Pediatrics Year: 2022 Document Type: Article