Role of medical comorbidity in the association between psychiatric disorders and mortality among patients with COVID-19.
Soc Psychiatry Psychiatr Epidemiol
; 57(8): 1727-1730, 2022 Aug.
Article
in English
| MEDLINE | ID: covidwho-1756779
ABSTRACT
We examined whether excess chronic medical comorbidity mediated excess COVID-19 inpatient mortality among people with mental disorders in the early phase of the pandemic, a question with important implications for public health and clinical decision-making. Using records of 2599 COVID-19 hospitalized patients, we conducted a formal causal mediation analysis to estimate the extent to which chronic comorbidity mediates the association between mental disorders and COVID-19 mortality. The Odds Ratio (95% CI) for Natural Indirect Effect and Controlled Direct Effect were 1.07(1.02, 1.14) and 1.40 (1.00, 1.95), respectively, suggesting that a large proportion of excess COVID-19 mortality among people with mental disorders may be explained by factors other than comorbidity.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Mental Disorders
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Qualitative research
Limits:
Humans
Language:
English
Journal:
Soc Psychiatry Psychiatr Epidemiol
Journal subject:
Social Sciences
/
Epidemiology
/
Psychiatry
Year:
2022
Document Type:
Article
Affiliation country:
S00127-022-02271-5
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