Household air pollution from wood-burning cookstoves and C-reactive protein among women in rural Honduras.
Int J Hyg Environ Health
; 241: 113949, 2022 04.
Article
in English
| MEDLINE | ID: covidwho-1757396
ABSTRACT
Household air pollution from solid fuel combustion was estimated to cause 2.31 million deaths worldwide in 2019; cardiovascular disease is a substantial contributor to the global burden. We evaluated the cross-sectional association between household air pollution (24-h gravimetric kitchen and personal particulate matter (PM2.5) and black carbon (BC)) and C-reactive protein (CRP) measured in dried blood spots among 107 women in rural Honduras using wood-burning traditional or Justa (an engineered combustion chamber) stoves. A suite of 6 additional markers of systemic injury and inflammation were considered in secondary analyses. We adjusted for potential confounders and assessed effect modification of several cardiovascular-disease risk factors. The median (25th, 75th percentiles) 24-h-average personal PM2.5 concentration was 115 µg/m3 (65,154 µg/m3) for traditional stove users and 52 µg/m3 (39, 81 µg/m3) for Justa stove users; kitchen PM2.5 and BC had similar patterns. Higher concentrations of PM2.5 and BC were associated with higher levels of CRP (e.g., a 25% increase in personal PM2.5 was associated with a 10.5% increase in CRP [95% CI 1.2-20.6]). In secondary analyses, results were generally consistent with a null association. Evidence for effect modification between pollutant measures and four different cardiovascular risk factors (e.g., high blood pressure) was inconsistent. These results support the growing evidence linking household air pollution and cardiovascular disease.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Air Pollution, Indoor
/
Air Pollutants
/
Air Pollution
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Female
/
Humans
Country/Region as subject:
Central America
/
Honduras
Language:
English
Journal:
Int J Hyg Environ Health
Journal subject:
Environmental Health
/
Public Health
Year:
2022
Document Type:
Article
Affiliation country:
J.ijheh.2022.113949
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