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SARS-CoV-2 Spike Protein in Intestinal Cells of a Patient with Coronavirus Disease 2019 Multisystem Inflammatory Syndrome.
Mayordomo-Colunga, Juan; Vivanco-Allende, Ana; López-Alonso, Inés; López-Martínez, Cecilia; Fernández-Vega, Iván; Gil-Peña, Helena; Rey, Corsino.
  • Mayordomo-Colunga J; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain; Centro de Investigación Biomédica En Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:
  • Vivanco-Allende A; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
  • López-Alonso I; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain; Centro de Investigación Biomédica En Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.
  • López-Martínez C; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain; Centro de Investigación Biomédica En Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
  • Fernández-Vega I; Department of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain.
  • Gil-Peña H; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
  • Rey C; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain; Department of Pediatrics, University of Oviedo, Oviedo, Spain; Maternal and Child Health and Development Research Network, Institute of
J Pediatr ; 243: 214-218.e5, 2022 04.
Article in English | MEDLINE | ID: covidwho-1757591
ABSTRACT
A previously healthy 12-year-old boy had severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related multisystem inflammatory syndrome (MIS-C) that was rapidly fatal. Autopsy revealed the presence of a large intracardiac thrombus. SARS-CoV-2 spike protein was detected in intestinal cells, supporting the hypothesis that viral presence in the gut may be related to the immunologic response of MIS-C.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / COVID-19 / Intestines Type of study: Case report / Prognostic study Topics: Long Covid Limits: Child / Humans / Male Language: English Journal: J Pediatr Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / COVID-19 / Intestines Type of study: Case report / Prognostic study Topics: Long Covid Limits: Child / Humans / Male Language: English Journal: J Pediatr Year: 2022 Document Type: Article