Your browser doesn't support javascript.
Subacute Thyroiditis Following SARS-CoV-2 Vaccines: Six Cases Report and Review of the Literature.
Kurtulmus, Neslihan; Kayikci, Kubra.
  • Kurtulmus N; Department of Endocrinology and Metabolism, Acibadem Maslak Hospital, Istanbul, Turkey.
  • Kayikci K; Medical School, Bezmialem Vakif University, Istanbul, Turkey.
Horm Metab Res ; 54(8): 556-561, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1758430
ABSTRACT
Subacute thyroiditis (SAT) is an inflammatory disease of the thyroid that develops following viral upper respiratory tract infections. SARS-CoV-2 virus, the cause of COVID-19, binds to the Angiotensin-Converting Enzyme-2 (ACE2) molecule expressed on the target cell surface. Thyroid gland shows high levels of ACE2 expression. The cases of SARS-CoV-2-related subacute thyroiditis and Graves' disease have been reported. It has recently been noted that vaccines for SARS-CoV-2 also induce autoimmune and inflammatory reactions. We present six (4 male, 2 female) cases of SAT that developed after mRNA and inactivated SARS-CoV-2 vaccines. And we have reviewed the literature. SAT was seen in 5 patients after mRNA vaccine, in one after inactivated vaccine. Their clinic and laboratory findings suggested to SAT. They were treated with nonsteroid anti-inflamatory drugs and/or methylprednisolone.They recovered within few weeks. Out patients did not have permanent hypothyroidism after SAT. The history of SARS-CoV-2 vaccination should be questioned in patients with subacute thyroiditis in pandemic days.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Thyroiditis, Subacute / Graves Disease / COVID-19 Type of study: Case report / Observational study / Prognostic study Topics: Vaccines Limits: Female / Humans / Male Language: English Journal: Horm Metab Res Year: 2022 Document Type: Article Affiliation country: A-1804-9561

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Thyroiditis, Subacute / Graves Disease / COVID-19 Type of study: Case report / Observational study / Prognostic study Topics: Vaccines Limits: Female / Humans / Male Language: English Journal: Horm Metab Res Year: 2022 Document Type: Article Affiliation country: A-1804-9561