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Rapid review for the anti-coronavirus effect of remdesivir.
Li, Ziyi; Wang, Xiaojie; Cao, Donglin; Sun, Ruilin; Li, Cheng; Li, Guowei.
  • Li Z; Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
  • Wang X; Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
  • Cao D; Hospital Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
  • Sun R; Department of Pulmonary and Critical Care Medicine, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
  • Li C; Guangdong Traditional Medical and Sports Injury Rehabilitation Research Institute, Guangdong Second Provincial General Hospital, Guangzhou, China.
  • Li G; Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Drug Discov Ther ; 14(2): 73-76, 2020.
Article in English | MEDLINE | ID: covidwho-176020
ABSTRACT
The outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from well-designed and adequately-powered clinical trials for further clarification.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Pneumonia, Viral / Adenosine Monophosphate / Coronavirus Infections / Alanine Type of study: Experimental Studies / Prognostic study / Randomized controlled trials / Reviews Topics: Traditional medicine Limits: Animals / Humans Language: English Journal: Drug Discov Ther Year: 2020 Document Type: Article Affiliation country: Ddt.2020.01015

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Pneumonia, Viral / Adenosine Monophosphate / Coronavirus Infections / Alanine Type of study: Experimental Studies / Prognostic study / Randomized controlled trials / Reviews Topics: Traditional medicine Limits: Animals / Humans Language: English Journal: Drug Discov Ther Year: 2020 Document Type: Article Affiliation country: Ddt.2020.01015