[Diagnosis and treatment of COVID-19 in intensive care units]. / Diagnostik und Therapie von COVID-19 auf der Intensivstation.
Med Klin Intensivmed Notfmed
; 117(3): 177-186, 2022 Apr.
Article
in German
| MEDLINE | ID: covidwho-1763329
ABSTRACT
Treatment of coronavirus disease 2019 (COVID-19) is particularly challenging due to the rapid scientific advances and the often significant hypoxemia. Use of high-flow oxygen, noninvasive mask ventilation, and the technique of awake proning can sometimes avoid the need for intubation. Mechanical ventilation follows the principles of ventilation for acute respiratory distress syndrome (ARDS; lung protective ventilation) and is generally supplemented by consequent positioning therapy (with at least 16â¯h in prone position in multiple cycles). Antiviral therapy options such as remdesivir usually come too late for patients with COVID-19 in the ICU, the only exception being the administration of monoclonal antibodies for patients without seroconversion. The value of immunomodulatory therapy such as dexamethasone is undisputed. Interleukin6 antagonists, on the other hand, are rather problematic for ICU patients, and for Janus kinase inhibitors, data and experience are still insufficient in this context.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Noninvasive Ventilation
/
COVID-19
Topics:
Long Covid
Limits:
Humans
Language:
German
Journal:
Med Klin Intensivmed Notfmed
Year:
2022
Document Type:
Article
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