Enigma of COVID-19: is "multisystem inflammatory syndrome in adults" (MIS-A) predictable?
BMC Infect Dis
; 22(1): 300, 2022 Mar 28.
Article
in English
| MEDLINE | ID: covidwho-1765440
ABSTRACT
BACKGROUND:
Severe inflammation and one or more extrapulmonary organ dysfunctions have been reported and this clinical picture is defined as "multisystem inflammatory syndrome in adults" (MIS-A) in severe coronavirus disease-2019 (COVID-19). We aimed to determine the effect of LDH/lymphocyte ratio (LLR) on the development of MIS-A.METHODS:
The data of 2333 patients were retrospectively analyzed.RESULTS:
MIS-A rate was found to be 9.9% and MIS-A related mortality was 35.3%. LRR level above 0.24 was found to predict MIS-A development with 70% sensitivity and 65.2% specificity. The risk of MIS-A development was found to be 3.64 times higher in those with LRR levels above 0.24 compared to those with 0.24 and below. In patients with MIS-A, LRR level above 0.32 predicts mortality with 78% sensitivity and 70% specificity.CONCLUSIONS:
Early detection of MIS-A with high sensitivity and specificity in a practical ratio is very important in terms new studies.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Malnutrition
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
Language:
English
Journal:
BMC Infect Dis
Journal subject:
Communicable Diseases
Year:
2022
Document Type:
Article
Affiliation country:
S12879-022-07303-8
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