Homocysteine as a marker for predicting disease severity in patients with COVID-19.
Biomark Med
; 16(7): 559-568, 2022 05.
Article
in English
| MEDLINE | ID: covidwho-1765636
ABSTRACT
Aim:
Our study was designed on the hypothesis that homocysteine levels are a prognostic parameter that can predict the severity of COVID-19 disease. Materials &methods:
117 COVID-19 patients and 34 non COVID-19 individuals were included in the study. Receiver operating characteristic (ROC) analysis was performed for homocysteine, D-dimer and monocyte/lymphocyte ratio (MLR) levels.Results:
According to the ROC analysis, in COVID-19 patients group, Area under curve (AUC) values were 0.835 for homocysteine, 0.859 for D-dimer and 0.882 for MLR. According to the ROC analysis, in which homocysteine, MLR and D-dimer parameters were evaluated together, AUC values were 0.951 in the mild disease group, 1000 in severe disease group and 0.967 in COVID-19 patients group.Conclusion:
It was concluded that homocysteine level is an important parameter in the follow-up of COVID-19 disease.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Biomark Med
Journal subject:
Biochemistry
/
Medicine
Year:
2022
Document Type:
Article
Affiliation country:
Bmm-2021-0688
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