Interactions between the Re-Emerging Pathogen Corynebacterium diphtheriae and Host Cells.
Int J Mol Sci
; 23(6)2022 Mar 18.
Article
in English
| MEDLINE | ID: covidwho-1765734
ABSTRACT
Corynebacterium diphtheriae, the etiological agent of diphtheria, is a re-emerging pathogen, responsible for several thousand deaths per year. In addition to diphtheria, systemic infections, often by non-toxigenic strains, are increasingly observed. This indicates that besides the well-studied and highly potent diphtheria toxin, various other virulence factors may influence the progression of the infection. This review focuses on the known components of C. diphtheriae responsible for adhesion, invasion, inflammation, and cell death, as well as on the cellular signaling pathways activated upon infection.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Corynebacterium diphtheriae
/
Diphtheria
Type of study:
Etiology study
Limits:
Humans
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Ijms23063298
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