Chiral Molecules: Properties, Synthesis and Analysis

ABSTRACT

In this paper, the authors describe a set of dynamic chromatography experiments on chiral HPLC columns, and in the range from room temperature to −50 °C for four 1,4-benzodiazepines, extracting the data for the best analytical conditions for their enantiomeric separation. [...]I want to express my great appreciation for the efficient assistance provided to me by Amelia Sun and the Editorial Office of Symmetry. Abbreviations PXRD powder X-ray diffraction;ESI electrospray ionization;HPLC high-performance liquid chromatography;DFT density functional theory;VCD vibrational circular dichroism;ECD electronic circular dichroism;CD circular dichroism.