Role of Melatonin as a Biomarker and Therapeutic agent in modulating the circadian rhythm in Covid-19

ABSTRACT

Calling Covid-19 a viral disease would be an understatement. The worldwide impact this pandemic has caused in every sphere of human life is remarkable and so is the pace at which treatment modalities and immunisation agents were formulised for it. More so, the severe complications of this disease can be devastating and fatal, therefore a number of pharmaceutical agents have been studied that have shown response in the critically ill. This article throws light upon how melatonin can be a safe and effective adjuvant pharmaceutical agent against Covid-19. Melatonin is one of the hormones that controls the bodily clock, which in turn has a crucial role to play in the pathogenesis of Covid-19. Yoga asanas can also aid in suppressing the aggravated immune response and inflammatory process in this disease. Anxiety due to the disease itself and other social factors related to it, is another reason for disturbed sleep and hence poor immune response in alleviating the effects of Covid-19.