A risk score for predicting death in COVID-19 in-hospital infection: A Brazilian single-center study.
J Clin Ultrasound
; 50(5): 604-610, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1767355
ABSTRACT
BACKGROUND:
There is a paucity of information about Brazilian COVID-19 in-hospital mortality probability of death combining risk factors.OBJECTIVE:
We aimed to correlate COVID-19 Brazilian in-hospital patients' mortality to demographic aspects, biomarkers, tomographic, echocardiographic findings, and clinical events.METHODS:
A prospective study, single tertiary center in Brazil, consecutive patients hospitalized with COVID-19. We analyzed the data from 111 patients from March to August 2020, performed a complete transthoracic echocardiogram, chest thoracic tomographic (CT) studies, collected biomarkers and correlated to in-hospital mortality.RESULTS:
Mean age of the patients 67 ± 17 years old, 65 (58.5%) men, 29 (26%) presented with systemic arterial hypertension, 18 (16%) with diabetes, 11 (9.9%) with chronic obstructive pulmonary disease. There was need for intubation and mechanical ventilation of 48 (43%) patients, death occurred in 21/111 (18.9%) patients. Multiple logistic regression models correlated variables with mortality age (OR 1.07; 95% CI 1.02-1.12; p 0.012; age >74 YO AUC ROC curve 0.725), intubation need (OR 23.35; 95% CI 4.39-124.36; p < 0.001), D dimer (OR 1.39; 95% CI 1.02-1.89; p 0.036; value >1928.5 ug/L AUC ROC curve 0.731), C-reactive protein (OR 1.18; 95% CI 1.05-1.32; p < 0.005; value >29.35 mg/dl AUC ROC curve 0.836). A risk score was created to predict intrahospital probability of death, by the equation 3.6 (age >75 YO) + 66 (intubation need) + 28 (C-reactive protein >29) + 2.2 (D dimer >1900).CONCLUSIONS:
A novel and original risk score were developed to predict the probability of death in Covid 19 in-hospital patients concerning combined risk factors.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Hospital Mortality
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
J Clin Ultrasound
Year:
2022
Document Type:
Article
Affiliation country:
Jcu.23195
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