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The epidemiology, diagnosis and treatment of COVID-19.
Zhai, Pan; Ding, Yanbing; Wu, Xia; Long, Junke; Zhong, Yanjun; Li, Yiming.
  • Zhai P; Department of Neurology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430073, Hubei, China.
  • Ding Y; Department of Neurology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430073, Hubei, China.
  • Wu X; Department of Respiratory Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430073, Hubei, China.
  • Long J; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
  • Zhong Y; ICU Center, The Second Xiangya Hospital, Central South University, Furong, Changsha, Hunan, 41001, China.
  • Li Y; Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China. Electronic address: lym-fly@whu.edu.cn.
Int J Antimicrob Agents ; 55(5): 105955, 2020 May.
Article in English | MEDLINE | ID: covidwho-17681
ABSTRACT
In December 2019, the outbreak of the novel coronavirus disease (COVID-19) in China spread worldwide, becoming an emergency of major international concern. SARS-CoV-2 infection causes clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus. Human-to-human transmission via droplets, contaminated hands or surfaces has been described, with incubation times of 2-14 days. Early diagnosis, quarantine, and supportive treatments are essential to cure patients. This paper reviews the literature on all available information about the epidemiology, diagnosis, isolation and treatments of COVID-19. Treatments, including antiviral agents, chloroquine and hydroxychloroquine, corticosteroids, antibodies, convalescent plasma transfusion and vaccines, are discussed in this article. In addition, registered trials investigating treatment options for COVID-19 infection are listed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Int J Antimicrob Agents Year: 2020 Document Type: Article Affiliation country: J.ijantimicag.2020.105955

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Int J Antimicrob Agents Year: 2020 Document Type: Article Affiliation country: J.ijantimicag.2020.105955