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Undernourished patients do not have increased risk of severe COVID-19 outcomes.
Fneich, Ahmad; Poinsot, Pierre; Elias, Christelle; Restier, Lioara; Vanhems, Philippe; Wallet, Florent; Caussy, Cyrielle; Duclos, Antoine; Peretti, Noël.
  • Fneich A; Univ Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, France.
  • Poinsot P; Univ Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, France.
  • Elias C; Univ Lyon, CarMeN Laboratory, INRAE, UMR1397, INSERM, UMR1060, F-69310, Pierre-Bénite, France.
  • Restier L; Emerging Pathogens Laboratory- Fondation Mérieux, Lyon, France.
  • Vanhems P; Univ Lyon, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR 5308, ENS Lyon, F-69008 Lyon, France.
  • Wallet F; Univ Lyon, Hospices Civil de Lyon, Infection Control and Epidemiology Unit, Hôpital Croix Rousse, F-69004 Lyon, France.
  • Caussy C; Univ Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, France.
  • Duclos A; Emerging Pathogens Laboratory- Fondation Mérieux, Lyon, France.
  • Peretti N; Univ Lyon, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR 5308, ENS Lyon, F-69008 Lyon, France.
Clin Nutr Open Sci ; 44: 9-14, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1768432
ABSTRACT

Background:

Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet.

Methods:

We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection.

Results:

Risk of intensive care unit admission and invasive mechanical ventilation requirement was not significantly different between undernutrition and normoweight sub-groups, but increased in excessive weight sub-group (ODDR (IC 95%) 1.048 (1.011-1.086), p = 0.011). Risk of death was the same in all sub-groups.

Conclusion:

Undernutrition didn't appear as a factor of severe outcomes in covid-19 infection.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Clin Nutr Open Sci Year: 2022 Document Type: Article Affiliation country: J.nutos.2022.03.002

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Clin Nutr Open Sci Year: 2022 Document Type: Article Affiliation country: J.nutos.2022.03.002