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High Asymptomatic Carriage With the Omicron Variant in South Africa.
Garrett, Nigel; Tapley, Asa; Andriesen, Jessica; Seocharan, Ishen; Fisher, Leigh H; Bunts, Lisa; Espy, Nicole; Wallis, Carole L; Randhawa, April Kaur; Miner, Maurine D; Ketter, Nzeera; Yacovone, Margaret; Goga, Ameena; Huang, Yunda; Hural, John; Kotze, Philip; Bekker, Linda Gail; Gray, Glenda E; Corey, Lawrence.
  • Garrett N; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
  • Tapley A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Andriesen J; University of Washington School of Medicine, Seattle, Washington, USA.
  • Seocharan I; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Fisher LH; South African Medical Research Council, Cape Town, South Africa.
  • Bunts L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Espy N; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Wallis CL; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Randhawa AK; Bio Analytical Research Corporation South Africa and Lancet Laboratories, Johannesburg, South Africa.
  • Miner MD; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Ketter N; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Yacovone M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Goga A; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Huang Y; South African Medical Research Council, Cape Town, South Africa.
  • Hural J; University of Pretoria, Pretoria, South Africaand.
  • Kotze P; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Bekker LG; Department of Global Health, University of Washington, Seattle, Washington, USA.
  • Gray GE; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Corey L; Qhakaza Mbokodo Research Clinic, Ladysmith, South Africa.
Clin Infect Dis ; 75(1): e289-e292, 2022 08 24.
Article in English | MEDLINE | ID: covidwho-1769236
ABSTRACT
We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Variants Limits: Humans Country/Region as subject: Africa Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Variants Limits: Humans Country/Region as subject: Africa Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid