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Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19.
Houchen-Wolloff, Linzy; Poinasamy, Krisnah; Holmes, Kate; Tarpey, Maryrose; Hastie, Claire; Raihani, Kelly; Rogers, Natalie; Smith, Nikki; Adams, Dawn; Burgess, Paul; Clark, Jean; Cranage, Clare; Desai, Mahadev; Geary, Nicola; Gill, Rhyan; Mangwani, Jitendra; Staunton, Lily; Berry, Colin; Bolton, Charlotte E; Chalder, Trudie; Chalmers, James; De Soyza, Anthony; Elneima, Omer; Geddes, John; Heller, Simon; Ho, Ling-Pei; Jacob, Joseph; McAuley, Hamish; Parmar, Aarti; Quint, Jennifer K; Raman, Betty; Rowland, Matthew; Singapuri, Amisha; Singh, Sally J; Thomas, David; Toshner, Mark R; Wain, Louise V; Horsley, Alex Robert; Marks, Michael; Brightling, Christopher E; Evans, Rachael A.
  • Houchen-Wolloff L; Respiratory Sciences, University of Leicester, Leicester, UK.
  • Poinasamy K; NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.
  • Holmes K; Research and Innovation Advocacy, Asthma & Lung UK, London, UK.
  • Tarpey M; Office for Clinical Research Infrastructure (NOCRI), National Institute for Health Research, London, UK.
  • Hastie C; James Lind Alliance, University of Southampton, Southampton, UK.
  • Raihani K; Long Covid Support, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Rogers N; Long Covid Support, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Smith N; Long Covid Support, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Adams D; Long Covid Support, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Burgess P; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Clark J; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Cranage C; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Desai M; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Geary N; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Gill R; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Mangwani J; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Staunton L; Leicester Orthopaedic Research Network, University Hospitals of Leicester NHS Trust, Leicester, UK.
  • Berry C; Patient and Public Involvement Group, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester, UK.
  • Bolton CE; British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
  • Chalder T; Respiratory Medicine, NIHR Nottingham Biomedical Research Centre Respiratory Theme, University of Nottingham, Nottingham, UK.
  • Chalmers J; Pyschological Medicine, King's College London, London, UK.
  • De Soyza A; Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.
  • Elneima O; Lung Biology and Transplantation Group, Newcastle University, Newcastle upon Tyne, UK.
  • Geddes J; Respiratory Sciences, University of Leicester, Leicester, UK.
  • Heller S; NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.
  • Ho LP; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Jacob J; Department of Oncology and Metabolism, The University of Sheffield, Sheffield, UK.
  • McAuley H; Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, UK.
  • Parmar A; Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford, UK.
  • Quint JK; Centre for Medical Imaging and Computing, University College London, London, UK.
  • Raman B; Department of Respiratory Medicine, University College London, London, UK.
  • Rowland M; Respiratory Sciences, University of Leicester, Leicester, UK.
  • Singapuri A; NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.
  • Singh SJ; Respiratory Sciences, University of Leicester, Leicester, UK.
  • Thomas D; NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.
  • Toshner MR; Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London, London, UK.
  • Wain LV; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Horsley AR; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  • Marks M; NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.
  • Brightling CE; Respiratory Sciences, University of Leicester, Leicester, UK.
  • Evans RA; NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.
Thorax ; 77(7): 717-720, 2022 07.
Article in English | MEDLINE | ID: covidwho-1769953
ABSTRACT
Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Adult / Humans Language: English Journal: Thorax Year: 2022 Document Type: Article Affiliation country: Thoraxjnl-2021-218582

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Adult / Humans Language: English Journal: Thorax Year: 2022 Document Type: Article Affiliation country: Thoraxjnl-2021-218582