Fugitive Aerosol Therapy Emissions during Mechanical Ventilation: In Vitro Assessment of the Effect of Tidal Volume and Use of Protective Filters
Aerosol and Air Quality Research
; 20(12), 2020.
Article
in English
| ProQuest Central | ID: covidwho-1771374
ABSTRACT
Background:
During mechanical ventilation of a patient requiring ventilatory support, bystanders could potentially be exposed to aerosolised drug.Methods:
Fugitive drug aerosol emissions during simulated adult mechanical ventilation was assessed on a dual limb circuit. Tidal volume was set at 270 mL and 820 mL. The use of a protective filter on the exhalation port of the mechanical ventilator was assessed.Results:
Higher fugitive aerosol mass concentrations in the local environment were associated with larger tidal volume (0.077 (0.073, 0.091) mg m–3 at Vt = 820 mL vs. 0.062 (0.056, 0.065) mg m–3 at Vt = 270 mL) when no protective filter was used. The range of mass median aerodynamic diameters recorded was from 0.93 to 2.96 µm. When a filter was placed on the exhalation port of the mechanical ventilator, no fugitive emissions were recorded.Conclusion:
This study confirms that an appropriate filtration protocol mitigates the risk of fugitive emissions being released when patients undergo aerosol therapy during mechanical ventilation. A larger tidal volume resulted in higher fugitive aerosol mass.
Environmental Studies--Pollution; Aerosols; Protective filters; Exposure; Fugitive; Exhaled air; Ventilation; Humidity; Ventilators; Emissions; Severe acute respiratory syndrome coronavirus 2; Antibiotics; Exhalation; Respiratory distress syndrome; Tracheotomy; Medical research; Ostomy; Respiratory therapy; Circuits; Critical care; Drug dosages; United States--US; Switzerland
Full text:
Available
Collection:
Databases of international organizations
Database:
ProQuest Central
Type of study:
Experimental Studies
Language:
English
Journal:
Aerosol and Air Quality Research
Year:
2020
Document Type:
Article
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