The Heterocycles in the Context of COVID-19 (Part 1): a Review with Highlights of the Pandemic

ABSTRACT

This article is a mirror of the initial clippings of a project junior scientific initiation project and aims to make available a scientific text, in Portuguese language, built in the light of the main highlights that brought the chloroquine and hydroxychloroquine into the spotlight of the current pandemic context. In view of this context, the objective of this article, of an eminently theoretical nature, is to contribute to the delimitation of fundamental concepts in the field of organic chemistry. The methodology adopted for this descriptive and exploratory research, with a qualitative approach, consisted of systematically reviewing the literature, using indexed databases, to contextualize factual points about the historical origin (natural and synthetic) and the pharmacological properties of heterocycles correlated to the theme of COVID-19 pandemic. We approach concepts and structural chemical formulas that support the area of organic chemistry and, more specifically, heterocyclic chemistry. And, through this compilation, we present a way of quick access to the recent information anchored in journals of national and international impact.