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Possible use of the mucolytic drug, bromhexine hydrochloride, as a prophylactic agent against SARS-CoV-2 infection based on its action on the Transmembrane Serine Protease 2.
Habtemariam, Solomon; Nabavi, Seyed Fazel; Ghavami, Saeid; Cismaru, Cosmin Andrei; Berindan-Neagoe, Ioana; Nabavi, Seyed Mohammad.
  • Habtemariam S; Pharmacognosy Research Laboratories and Herbal Analysis Services, University of Greenwich, Central Avenue, Chatham-Maritime, Kent ME4 4TB, United Kingdom.
  • Nabavi SF; Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Ghavami S; Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
  • Cismaru CA; Research Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Functional Sciences, Immunology and Allergology, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
  • Berindan-Neagoe I; Research Center for Functional Genomics, Biomedicine and Translational Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania; The Research Center for Advanced Medicine- Medfuture- "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania; The Function
  • Nabavi SM; Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: Nabavi208@gmail.com.
Pharmacol Res ; 157: 104853, 2020 07.
Article in English | MEDLINE | ID: covidwho-177281

Full text: Available Collection: International databases Database: MEDLINE Main subject: Bromhexine / Severe acute respiratory syndrome-related coronavirus Limits: Humans Language: English Journal: Pharmacol Res Journal subject: Pharmacology Year: 2020 Document Type: Article Affiliation country: J.phrs.2020.104853

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bromhexine / Severe acute respiratory syndrome-related coronavirus Limits: Humans Language: English Journal: Pharmacol Res Journal subject: Pharmacology Year: 2020 Document Type: Article Affiliation country: J.phrs.2020.104853